Model info
| Transcription factor | RUNX2 | ||||||||
| Model | RUNX2_HUMAN.H10DI.C | ||||||||
| Model type | Dinucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Origin | ChIP-Seq | ||||||||
| Model length | 23 | ||||||||
| Quality | C | ||||||||
| Consensus | ndbKKdbbdbTGTGGYYKbbdbb | ||||||||
| wAUC | 0.8378369163039524 | ||||||||
| Best AUC | 0.8378369163039524 | ||||||||
| Benchmark datasets | 1 | ||||||||
| Aligned words | 568 | ||||||||
| TF family | Runt-related factors{6.4.1} | ||||||||
| TF subfamily | Runx2 (PEBP2alphaA, CBF-alpha1){6.4.1.0.1} | ||||||||
| HGNC | 10472 | ||||||||
| EntrezGene | 860 | ||||||||
| UniProt ID | RUNX2_HUMAN | ||||||||
| UniProt AC | Q13950 | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
|
PCM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | 10.665 | 10.729 | 36.721 | 28.997 | 10.927 | 6.094 | 23.663 | 42.53 | 17.948 | 10.473 | 58.403 | 66.845 | 7.773 | 7.984 | 82.636 | 77.612 |
| 02 | 9.879 | 6.537 | 18.741 | 12.156 | 9.641 | 2.514 | 6.971 | 16.154 | 23.976 | 33.729 | 110.361 | 33.357 | 20.281 | 26.888 | 91.573 | 77.243 |
| 03 | 5.835 | 6.546 | 24.237 | 27.159 | 8.413 | 3.402 | 7.217 | 50.636 | 17.113 | 4.815 | 62.283 | 143.434 | 4.966 | 3.305 | 59.45 | 71.189 |
| 04 | 4.003 | 0.0 | 22.407 | 9.916 | 2.291 | 2.212 | 2.415 | 11.15 | 13.06 | 7.532 | 88.379 | 44.214 | 11.496 | 19.746 | 171.872 | 89.306 |
| 05 | 7.659 | 2.949 | 13.091 | 7.151 | 15.443 | 9.862 | 0.992 | 3.193 | 21.843 | 50.694 | 142.566 | 69.97 | 28.381 | 8.01 | 70.88 | 47.315 |
| 06 | 8.481 | 13.239 | 30.833 | 20.772 | 7.83 | 24.597 | 5.188 | 33.9 | 28.814 | 33.177 | 58.903 | 106.634 | 6.673 | 12.522 | 57.933 | 50.501 |
| 07 | 9.314 | 9.385 | 24.803 | 8.298 | 22.19 | 38.233 | 9.519 | 13.593 | 19.499 | 17.166 | 91.899 | 24.293 | 19.69 | 17.044 | 115.689 | 59.384 |
| 08 | 15.554 | 4.2 | 26.286 | 24.654 | 19.373 | 9.422 | 14.318 | 38.715 | 20.655 | 27.704 | 112.051 | 81.5 | 9.769 | 13.278 | 35.742 | 46.779 |
| 09 | 4.893 | 23.065 | 18.141 | 19.252 | 7.052 | 18.468 | 7.011 | 22.073 | 16.018 | 83.61 | 38.994 | 49.775 | 11.892 | 61.328 | 40.433 | 77.996 |
| 10 | 0.0 | 0.986 | 5.017 | 33.851 | 4.279 | 15.728 | 3.749 | 162.716 | 0.765 | 7.121 | 4.256 | 92.437 | 2.741 | 8.007 | 11.158 | 147.19 |
| 11 | 0.763 | 0.0 | 7.021 | 0.0 | 1.949 | 0.0 | 24.696 | 5.197 | 0.799 | 0.919 | 22.462 | 0.0 | 2.713 | 8.814 | 376.385 | 48.283 |
| 12 | 0.763 | 0.0 | 0.0 | 5.461 | 0.0 | 0.0 | 0.0 | 9.732 | 23.49 | 23.777 | 13.497 | 369.8 | 1.912 | 0.0 | 0.876 | 50.692 |
| 13 | 1.111 | 0.0 | 25.054 | 0.0 | 0.0 | 0.0 | 23.777 | 0.0 | 0.0 | 0.879 | 13.494 | 0.0 | 0.0 | 0.0 | 434.553 | 1.132 |
| 14 | 0.0 | 0.0 | 1.111 | 0.0 | 0.879 | 0.0 | 0.0 | 0.0 | 1.91 | 1.505 | 491.027 | 2.435 | 0.0 | 0.0 | 1.132 | 0.0 |
| 15 | 0.0 | 0.0 | 0.0 | 2.789 | 0.0 | 0.0 | 0.0 | 1.505 | 3.787 | 100.233 | 65.877 | 323.373 | 0.0 | 0.0 | 0.0 | 2.435 |
| 16 | 0.674 | 0.0 | 0.0 | 3.113 | 3.704 | 15.806 | 0.0 | 80.723 | 7.595 | 16.926 | 1.892 | 39.463 | 6.543 | 41.246 | 58.491 | 223.823 |
| 17 | 2.948 | 0.0 | 3.323 | 12.245 | 40.7 | 1.733 | 5.582 | 25.963 | 11.647 | 0.0 | 19.802 | 28.934 | 35.941 | 9.451 | 76.214 | 225.517 |
| 18 | 8.83 | 11.869 | 50.943 | 19.594 | 2.637 | 5.716 | 0.0 | 2.831 | 12.093 | 10.003 | 34.951 | 47.874 | 28.652 | 37.201 | 98.426 | 128.38 |
| 19 | 8.937 | 0.0 | 23.164 | 20.111 | 14.299 | 21.331 | 7.61 | 21.55 | 23.997 | 23.675 | 78.857 | 57.79 | 13.734 | 19.154 | 98.361 | 67.429 |
| 20 | 7.288 | 12.041 | 33.661 | 7.977 | 18.208 | 12.625 | 5.982 | 27.344 | 27.637 | 17.009 | 100.479 | 62.867 | 7.607 | 4.958 | 82.517 | 71.797 |
| 21 | 11.824 | 4.179 | 23.852 | 20.886 | 11.372 | 11.117 | 5.216 | 18.929 | 17.882 | 21.386 | 89.147 | 94.225 | 5.889 | 29.138 | 67.909 | 67.049 |
| 22 | 11.932 | 9.541 | 14.989 | 10.504 | 16.405 | 16.168 | 5.026 | 28.22 | 17.442 | 41.862 | 53.912 | 72.909 | 29.292 | 15.296 | 78.434 | 78.068 |
PWM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | -1.052 | -1.046 | 0.159 | -0.074 | -1.028 | -1.585 | -0.274 | 0.305 | -0.545 | -1.069 | 0.62 | 0.754 | -1.355 | -1.329 | 0.965 | 0.902 |
| 02 | -1.125 | -1.519 | -0.503 | -0.925 | -1.149 | -2.389 | -1.458 | -0.648 | -0.261 | 0.075 | 1.253 | 0.064 | -0.426 | -0.148 | 1.067 | 0.898 |
| 03 | -1.626 | -1.518 | -0.251 | -0.138 | -1.279 | -2.122 | -1.426 | 0.478 | -0.592 | -1.805 | 0.684 | 1.514 | -1.777 | -2.148 | 0.637 | 0.816 |
| 04 | -1.975 | -4.4 | -0.328 | -1.122 | -2.469 | -2.499 | -2.423 | -1.009 | -0.855 | -1.385 | 1.032 | 0.343 | -0.979 | -0.452 | 1.695 | 1.042 |
| 05 | -1.369 | -2.249 | -0.853 | -1.434 | -0.692 | -1.127 | -3.132 | -2.179 | -0.353 | 0.479 | 1.508 | 0.799 | -0.095 | -1.326 | 0.812 | 0.411 |
| 06 | -1.272 | -0.842 | -0.013 | -0.402 | -1.348 | -0.236 | -1.736 | 0.08 | -0.08 | 0.059 | 0.628 | 1.219 | -1.5 | -0.896 | 0.612 | 0.475 |
| 07 | -1.182 | -1.175 | -0.228 | -1.293 | -0.337 | 0.199 | -1.161 | -0.817 | -0.464 | -0.589 | 1.071 | -0.248 | -0.455 | -0.596 | 1.3 | 0.636 |
| 08 | -0.685 | -1.931 | -0.171 | -0.234 | -0.471 | -1.171 | -0.766 | 0.212 | -0.408 | -0.119 | 1.268 | 0.951 | -1.136 | -0.839 | 0.133 | 0.399 |
| 09 | -1.79 | -0.299 | -0.535 | -0.477 | -1.447 | -0.517 | -1.453 | -0.343 | -0.657 | 0.976 | 0.219 | 0.461 | -0.946 | 0.668 | 0.255 | 0.907 |
| 10 | -4.4 | -3.137 | -1.767 | 0.079 | -1.914 | -0.675 | -2.034 | 1.64 | -3.312 | -1.438 | -1.919 | 1.076 | -2.314 | -1.327 | -1.008 | 1.54 |
| 11 | -3.313 | -4.4 | -1.452 | -4.4 | -2.606 | -4.4 | -0.232 | -1.734 | -3.283 | -3.187 | -0.325 | -4.4 | -2.323 | -1.235 | 2.477 | 0.431 |
| 12 | -3.313 | -4.4 | -4.4 | -1.688 | -4.4 | -4.4 | -4.4 | -1.14 | -0.281 | -0.269 | -0.824 | 2.46 | -2.621 | -4.4 | -3.22 | 0.479 |
| 13 | -3.049 | -4.4 | -0.218 | -4.4 | -4.4 | -4.4 | -0.269 | -4.4 | -4.4 | -3.217 | -0.824 | -4.4 | -4.4 | -4.4 | 2.621 | -3.035 |
| 14 | -4.4 | -4.4 | -3.049 | -4.4 | -3.217 | -4.4 | -4.4 | -4.4 | -2.622 | -2.816 | 2.743 | -2.416 | -4.4 | -4.4 | -3.035 | -4.4 |
| 15 | -4.4 | -4.4 | -4.4 | -2.298 | -4.4 | -4.4 | -4.4 | -2.816 | -2.025 | 1.157 | 0.739 | 2.326 | -4.4 | -4.4 | -4.4 | -2.416 |
| 16 | -3.393 | -4.4 | -4.4 | -2.201 | -2.045 | -0.67 | -4.4 | 0.941 | -1.377 | -0.603 | -2.63 | 0.231 | -1.518 | 0.275 | 0.621 | 1.958 |
| 17 | -2.25 | -4.4 | -2.143 | -0.918 | 0.261 | -2.702 | -1.668 | -0.183 | -0.966 | -4.4 | -0.449 | -0.076 | 0.138 | -1.168 | 0.884 | 1.966 |
| 18 | -1.233 | -0.948 | 0.484 | -0.46 | -2.347 | -1.645 | -4.4 | -2.285 | -0.93 | -1.113 | 0.111 | 0.422 | -0.086 | 0.172 | 1.139 | 1.404 |
| 19 | -1.222 | -4.4 | -0.295 | -0.434 | -0.767 | -0.376 | -1.375 | -0.366 | -0.26 | -0.274 | 0.918 | 0.609 | -0.807 | -0.482 | 1.138 | 0.762 |
| 20 | -1.416 | -0.934 | 0.073 | -1.33 | -0.531 | -0.888 | -1.603 | -0.132 | -0.121 | -0.598 | 1.159 | 0.693 | -1.375 | -1.778 | 0.963 | 0.825 |
| 21 | -0.952 | -1.935 | -0.266 | -0.397 | -0.99 | -1.012 | -1.731 | -0.493 | -0.549 | -0.374 | 1.04 | 1.095 | -1.617 | -0.069 | 0.77 | 0.757 |
| 22 | -0.943 | -1.159 | -0.721 | -1.066 | -0.633 | -0.648 | -1.765 | -0.101 | -0.573 | 0.289 | 0.54 | 0.84 | -0.064 | -0.702 | 0.913 | 0.908 |