Model info
| Transcription factor | ESR2 | ||||||||
| Model | ESR2_HUMAN.H10DI.A | ||||||||
| Model type | Dinucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Origin | ChIP-Seq | ||||||||
| Model length | 23 | ||||||||
| Quality | A | ||||||||
| Consensus | nnnRGGKCAvRSYGhCYYnvvnn | ||||||||
| wAUC | 0.8907731268124801 | ||||||||
| Best AUC | 0.8957125627381363 | ||||||||
| Benchmark datasets | 2 | ||||||||
| Aligned words | 517 | ||||||||
| TF family | Steroid hormone receptors (NR3){2.1.1} | ||||||||
| TF subfamily | ER-like receptors (NR3A&B){2.1.1.2} | ||||||||
| HGNC | 3468 | ||||||||
| EntrezGene | 2100 | ||||||||
| UniProt ID | ESR2_HUMAN | ||||||||
| UniProt AC | Q92731 | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
|
PCM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | 22.623 | 32.484 | 35.139 | 13.759 | 35.075 | 53.898 | 3.194 | 59.68 | 37.646 | 42.488 | 32.656 | 20.278 | 16.271 | 50.76 | 18.027 | 18.057 |
| 02 | 34.684 | 36.807 | 25.706 | 14.419 | 71.631 | 61.496 | 4.852 | 41.651 | 32.611 | 27.3 | 23.217 | 5.887 | 12.025 | 29.451 | 58.862 | 11.435 |
| 03 | 76.997 | 3.086 | 68.099 | 2.77 | 112.13 | 4.238 | 19.886 | 18.801 | 78.206 | 0.971 | 23.725 | 9.736 | 12.869 | 1.96 | 56.736 | 1.827 |
| 04 | 20.113 | 0.0 | 231.683 | 28.406 | 1.084 | 0.0 | 5.994 | 3.177 | 26.975 | 0.887 | 114.035 | 26.55 | 0.909 | 0.0 | 30.368 | 1.856 |
| 05 | 0.987 | 0.0 | 48.094 | 0.0 | 0.0 | 0.0 | 0.887 | 0.0 | 38.298 | 9.708 | 333.132 | 0.942 | 5.982 | 0.0 | 51.871 | 2.135 |
| 06 | 2.939 | 2.847 | 18.426 | 21.054 | 1.062 | 5.578 | 0.0 | 3.068 | 19.822 | 32.311 | 116.672 | 265.18 | 0.0 | 0.0 | 3.076 | 0.0 |
| 07 | 0.0 | 22.073 | 0.879 | 0.871 | 0.0 | 39.644 | 0.0 | 1.091 | 0.0 | 127.583 | 0.965 | 9.626 | 3.647 | 257.721 | 6.906 | 21.028 |
| 08 | 3.647 | 0.0 | 0.0 | 0.0 | 375.78 | 12.865 | 25.816 | 32.561 | 3.873 | 0.0 | 4.877 | 0.0 | 16.963 | 2.043 | 8.794 | 4.817 |
| 09 | 66.453 | 100.188 | 186.419 | 47.204 | 8.873 | 0.922 | 0.942 | 4.17 | 12.948 | 6.847 | 11.986 | 7.706 | 5.032 | 5.937 | 19.692 | 6.716 |
| 10 | 23.696 | 0.976 | 62.883 | 5.751 | 75.888 | 1.038 | 36.969 | 0.0 | 77.229 | 5.457 | 136.353 | 0.0 | 15.624 | 0.0 | 50.172 | 0.0 |
| 11 | 36.439 | 41.37 | 109.783 | 4.845 | 0.0 | 0.0 | 7.471 | 0.0 | 38.45 | 66.717 | 158.714 | 22.495 | 0.0 | 0.0 | 5.751 | 0.0 |
| 12 | 22.797 | 9.63 | 6.146 | 36.317 | 16.788 | 13.47 | 0.0 | 77.828 | 29.489 | 41.389 | 7.765 | 203.076 | 0.0 | 7.619 | 0.0 | 19.721 |
| 13 | 2.888 | 0.0 | 66.186 | 0.0 | 27.343 | 8.749 | 35.146 | 0.871 | 0.0 | 0.0 | 13.003 | 0.909 | 8.367 | 33.383 | 291.51 | 3.682 |
| 14 | 15.787 | 8.56 | 10.601 | 3.65 | 36.217 | 2.04 | 0.0 | 3.875 | 217.339 | 103.655 | 39.561 | 45.289 | 0.862 | 2.82 | 0.0 | 1.779 |
| 15 | 9.833 | 243.361 | 9.531 | 7.481 | 7.958 | 100.363 | 0.862 | 7.891 | 1.011 | 46.857 | 1.055 | 1.238 | 0.0 | 38.491 | 4.853 | 11.249 |
| 16 | 0.935 | 16.88 | 0.987 | 0.0 | 44.54 | 329.497 | 0.976 | 54.058 | 1.055 | 13.031 | 1.287 | 0.929 | 0.0 | 24.957 | 0.902 | 2.001 |
| 17 | 1.16 | 14.994 | 5.243 | 25.134 | 23.442 | 134.294 | 14.718 | 211.911 | 0.0 | 2.274 | 0.902 | 0.976 | 0.0 | 25.188 | 8.962 | 22.839 |
| 18 | 5.785 | 4.792 | 13.037 | 0.987 | 63.47 | 30.476 | 22.244 | 60.56 | 8.913 | 7.24 | 5.64 | 8.031 | 28.431 | 59.272 | 125.692 | 47.464 |
| 19 | 22.29 | 16.64 | 58.604 | 9.064 | 43.635 | 18.481 | 16.268 | 23.397 | 44.156 | 30.435 | 64.093 | 27.928 | 8.097 | 14.885 | 80.574 | 13.487 |
| 20 | 16.449 | 39.582 | 50.408 | 11.74 | 24.067 | 33.069 | 7.989 | 15.316 | 56.729 | 66.556 | 71.443 | 24.81 | 6.453 | 15.893 | 42.571 | 8.959 |
| 21 | 14.616 | 37.985 | 37.32 | 13.777 | 24.839 | 64.161 | 8.068 | 58.032 | 33.063 | 46.758 | 45.12 | 47.47 | 5.077 | 21.992 | 27.615 | 6.142 |
| 22 | 22.157 | 17.865 | 30.558 | 7.015 | 59.389 | 61.294 | 11.652 | 38.56 | 36.048 | 26.731 | 43.093 | 12.249 | 10.706 | 42.638 | 50.53 | 21.549 |
PWM
| AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01 | -0.303 | 0.054 | 0.132 | -0.789 | 0.13 | 0.556 | -2.163 | 0.657 | 0.2 | 0.32 | 0.059 | -0.41 | -0.626 | 0.496 | -0.525 | -0.524 |
| 02 | 0.119 | 0.178 | -0.177 | -0.743 | 0.838 | 0.687 | -1.782 | 0.3 | 0.058 | -0.117 | -0.277 | -1.602 | -0.92 | -0.043 | 0.643 | -0.968 |
| 03 | 0.91 | -2.193 | 0.788 | -2.289 | 1.285 | -1.907 | -0.429 | -0.484 | 0.926 | -3.132 | -0.256 | -1.124 | -0.854 | -2.585 | 0.607 | -2.644 |
| 04 | -0.418 | -4.387 | 2.009 | -0.078 | -3.052 | -4.387 | -1.585 | -2.168 | -0.129 | -3.196 | 1.301 | -0.145 | -3.179 | -4.387 | -0.012 | -2.63 |
| 05 | -3.121 | -4.387 | 0.443 | -4.387 | -4.387 | -4.387 | -3.196 | -4.387 | 0.217 | -1.126 | 2.371 | -3.154 | -1.587 | -4.387 | 0.518 | -2.513 |
| 06 | -2.237 | -2.265 | -0.504 | -0.373 | -3.067 | -1.652 | -4.387 | -2.199 | -0.432 | 0.049 | 1.324 | 2.143 | -4.387 | -4.387 | -2.196 | -4.387 |
| 07 | -4.387 | -0.327 | -3.202 | -3.209 | -4.387 | 0.251 | -4.387 | -3.047 | -4.387 | 1.413 | -3.136 | -1.135 | -2.044 | 2.115 | -1.452 | -0.374 |
| 08 | -2.044 | -4.387 | -4.387 | -4.387 | 2.492 | -0.854 | -0.173 | 0.056 | -1.989 | -4.387 | -1.778 | -4.387 | -0.585 | -2.551 | -1.221 | -1.789 |
| 09 | 0.764 | 1.172 | 1.792 | 0.424 | -1.213 | -3.169 | -3.154 | -1.922 | -0.848 | -1.46 | -0.923 | -1.347 | -1.748 | -1.594 | -0.439 | -1.478 |
| 10 | -0.257 | -3.128 | 0.709 | -1.624 | 0.896 | -3.084 | 0.182 | -4.387 | 0.913 | -1.673 | 1.48 | -4.387 | -0.665 | -4.387 | 0.485 | -4.387 |
| 11 | 0.168 | 0.293 | 1.264 | -1.784 | -4.387 | -4.387 | -1.377 | -4.387 | 0.221 | 0.768 | 1.631 | -0.308 | -4.387 | -4.387 | -1.624 | -4.387 |
| 12 | -0.295 | -1.134 | -1.562 | 0.164 | -0.595 | -0.81 | -4.387 | 0.921 | -0.041 | 0.294 | -1.34 | 1.877 | -4.387 | -1.358 | -4.387 | -0.437 |
| 13 | -2.252 | -4.387 | 0.76 | -4.387 | -0.116 | -1.226 | 0.132 | -3.209 | -4.387 | -4.387 | -0.844 | -3.179 | -1.269 | 0.081 | 2.238 | -2.035 |
| 14 | -0.655 | -1.247 | -1.042 | -2.043 | 0.162 | -2.552 | -4.387 | -1.989 | 1.945 | 1.206 | 0.249 | 0.383 | -3.215 | -2.273 | -4.387 | -2.665 |
| 15 | -1.114 | 2.058 | -1.144 | -1.376 | -1.317 | 1.174 | -3.215 | -1.325 | -3.103 | 0.417 | -3.072 | -2.953 | -4.387 | 0.222 | -1.782 | -0.984 |
| 16 | -3.159 | -0.59 | -3.121 | -4.387 | 0.367 | 2.36 | -3.128 | 0.559 | -3.072 | -0.842 | -2.923 | -3.164 | -4.387 | -0.206 | -3.185 | -2.568 |
| 17 | -3.002 | -0.705 | -1.71 | -0.199 | -0.268 | 1.464 | -0.723 | 1.92 | -4.387 | -2.46 | -3.185 | -3.128 | -4.387 | -0.197 | -1.203 | -0.293 |
| 18 | -1.618 | -1.794 | -0.841 | -3.121 | 0.718 | -0.009 | -0.319 | 0.672 | -1.208 | -1.407 | -1.642 | -1.308 | -0.077 | 0.65 | 1.398 | 0.43 |
| 19 | -0.317 | -0.604 | 0.639 | -1.192 | 0.346 | -0.501 | -0.626 | -0.269 | 0.358 | -0.01 | 0.728 | -0.095 | -1.3 | -0.712 | 0.955 | -0.808 |
| 20 | -0.615 | 0.25 | 0.489 | -0.943 | -0.242 | 0.072 | -1.313 | -0.685 | 0.607 | 0.765 | 0.836 | -0.212 | -1.516 | -0.648 | 0.322 | -1.204 |
| 21 | -0.73 | 0.209 | 0.191 | -0.788 | -0.211 | 0.729 | -1.304 | 0.629 | 0.072 | 0.415 | 0.379 | 0.43 | -1.74 | -0.33 | -0.106 | -1.562 |
| 22 | -0.323 | -0.534 | -0.006 | -1.437 | 0.652 | 0.684 | -0.95 | 0.224 | 0.157 | -0.138 | 0.334 | -0.902 | -1.032 | 0.323 | 0.492 | -0.35 |