Model info
| Transcription factor | ESR1 | ||||||||
| Model | ESR1_HUMAN.H10MO.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Origin | ChIP-Seq | ||||||||
| Model length | 17 | ||||||||
| Quality | A | ||||||||
| Consensus | hhAKGTCAvvvWRnYYh | ||||||||
| wAUC | 0.8377011813705364 | ||||||||
| Best AUC | 0.9165699033707648 | ||||||||
| Benchmark datasets | 22 | ||||||||
| Aligned words | 483 | ||||||||
| TF family | Steroid hormone receptors (NR3){2.1.1} | ||||||||
| TF subfamily | ER-like receptors (NR3A&B){2.1.1.2} | ||||||||
| HGNC | 3467 | ||||||||
| EntrezGene | 2099 | ||||||||
| UniProt ID | ESR1_HUMAN | ||||||||
| UniProt AC | P03372 | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
|
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 115.486 | 210.928 | 61.11 | 95.476 |
| 02 | 115.666 | 200.729 | 69.019 | 97.586 |
| 03 | 370.917 | 9.479 | 93.454 | 9.15 |
| 04 | 40.019 | 3.337 | 341.904 | 97.74 |
| 05 | 5.749 | 8.971 | 449.925 | 18.355 |
| 06 | 7.965 | 12.367 | 18.025 | 444.643 |
| 07 | 0.0 | 433.334 | 40.035 | 9.631 |
| 08 | 449.753 | 20.867 | 6.104 | 6.276 |
| 09 | 86.793 | 213.349 | 118.061 | 64.797 |
| 10 | 160.856 | 151.357 | 113.422 | 57.366 |
| 11 | 140.29 | 141.274 | 146.179 | 55.257 |
| 12 | 114.536 | 46.847 | 31.262 | 290.355 |
| 13 | 77.457 | 35.86 | 361.829 | 7.854 |
| 14 | 165.278 | 143.582 | 70.758 | 103.383 |
| 15 | 54.08 | 297.367 | 29.161 | 102.392 |
| 16 | 47.775 | 336.524 | 27.839 | 70.863 |
| 17 | 97.537 | 156.015 | 44.861 | 184.587 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.044 | 0.552 | -0.669 | -0.232 |
| 02 | -0.042 | 0.503 | -0.55 | -0.21 |
| 03 | 1.114 | -2.406 | -0.253 | -2.437 |
| 04 | -1.079 | -3.221 | 1.033 | -0.208 |
| 05 | -2.819 | -2.454 | 1.306 | -1.816 |
| 06 | -2.554 | -2.174 | -1.832 | 1.294 |
| 07 | -4.371 | 1.269 | -1.079 | -2.393 |
| 08 | 1.306 | -1.697 | -2.772 | -2.75 |
| 09 | -0.325 | 0.564 | -0.022 | -0.612 |
| 10 | 0.284 | 0.223 | -0.062 | -0.73 |
| 11 | 0.148 | 0.155 | 0.189 | -0.767 |
| 12 | -0.052 | -0.927 | -1.316 | 0.87 |
| 13 | -0.437 | -1.185 | 1.089 | -2.566 |
| 14 | 0.31 | 0.171 | -0.526 | -0.153 |
| 15 | -0.788 | 0.894 | -1.382 | -0.163 |
| 16 | -0.908 | 1.017 | -1.426 | -0.524 |
| 17 | -0.21 | 0.253 | -0.969 | 0.42 |